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What is Zopiclone?


Zopiclone is a type of sleeping pill that can be taken to treat bad bouts of insomnia.

It helps you fall asleep more quickly, and also helps stop you waking up during the night.

Zopiclone comes as tablets. It also comes as a liquid for people who find it hard to swallow tablets, but this has to be ordered specially by your doctor.

This medicine is only available on prescription.


Key facts of Zopiclone


Zopiclone takes around 1 hour to work.

Zopiclone is usually prescribed for just 2 to 4 weeks. This is because your body gets used to it quickly and after this time it’s unlikely to have the same effect. Your body can also become dependent on it.

Common side effects are a metallic taste in your mouth, a dry mouth, and daytime sleepiness.

Do not drink alcohol while you’re on zopiclone. Having them together can make you go into a deep sleep where you find it difficult to wake up.

Zopiclone is also called by the brand name Zimovane.


Who can and cannot take Zopiclone?


Zopiclone can be taken by adults over the age of 18.

It’s not suitable for some people.

To make sure zopiclone is safe for you, tell your doctor if you:

  • have had an allergic reaction to zopiclone or any other medicines in the past
  • have liver or kidney problems
  • have myasthenia gravis, a condition that causes muscle weakness
  • have breathing problems or sleep apnoea (where you stop breathing for short bouts while sleeping)
  • have had mental health problems
  • have had issues with alcoholism or drug abuse
  • are trying to get pregnant, already pregnant, or breastfeeding


How and when to take it?


Dosage and strength

Zopiclone tablets come in 2 different strengths: 3.75mg and 7.5mg.

The usual dose is to take a 7.5mg tablet just before you go to bed. It takes around 1 hour to work.

A lower dose of 3.75mg may be recommended to begin with if you’re over 65 years old or have kidney or liver problems.

Taking a lower dose in these cases reduces the risk of excessive sleepiness and other side effects.

Swallow the tablet whole. Do not crush or chew it. You can take zopiclone with or without food.

It’s important to take it exactly as your doctor has told you. You could be asked to take a tablet on only 2 or 3 nights each week, rather than every night.

What if I forget to take it?

If you forget to take it by bedtime, just start again the next night.

Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.

What if I take too much?

If you have taken more than your prescribed dose by accident, call your doctor for advice.

Important

Do not take more than your prescribed dose.


What are side effects of Zopiclone?


Not everyone will get side effects with zopiclone.

These common side effects happen in more than 1 in 100 people.

Talk to your doctor or pharmacist if these side effects bother you or do not go away:

  • a bitter or metallic taste in your mouth or a dry mouth
  • feeling sleepy or tired

Serious side effects

Serious side effects are rare, but you should call your doctor as soon as possible if you:

  • lose your memory – this is called amnesia
  • see or hear things that are not real – these are called hallucinations
  • fall over, especially if you’re elderly
  • think things that are not true – these are called delusions
  • feel low or sad – this could be a sign of depression

Serious allergic reaction

In rare cases, it’s possible to have a serious allergic reaction (anaphylaxis) to zopiclone.

These are not all the side effects of zopiclone. For a full list, see the leaflet inside your medicines packet.


How to cope with side effects?


What to do about:

  • a bitter or metallic taste in your mouth or a dry mouth – if this bothers you, try taking sips of water and keep some water by your bed at night. Using a mouthwash before bedtime may also help. Choose one that’s good for a dry mouth, as some can make a dry mouth worse.
  • feeling sleepy or tired – do not drive or use tools or machinery if you’re feeling this way. Do not drink any alcohol as this will make you feel more tired. If this does not help, talk to your doctor.


Is Zopiclone safe during Pregnancy?


Do not take zopiclone if you’re pregnant, as it may harm the developing baby. It can also cause side effects in newborn babies.

There’s some evidence that taking zopiclone can increase your risk of having a baby born early (before 37 weeks) and the baby having a lower birth weight.

Taking zopiclone right up to labor may increase the chance of the baby having withdrawal symptoms at birth.

For more information about how zopiclone can affect you and your baby during pregnancy.

Zopiclone and breastfeeding

Zopiclone passes into breast milk in small amounts.

If you have to take zopiclone, talk to your doctor or midwife about your feeding options.


Is it safe to take Zopiclone with other medicines?


Some medicines and zopiclone can interfere with each other and increase the chances of you having side effects.

Certain medicines may increase the drowsy-making (sedating) effects of zopiclone.

Speak to your doctor or pharmacist before starting on zopiclone if you take any of the following:

  • medicines to treat schizophrenia and bipolar disorder
  • medicines to treat depression
  • medicines for epilepsy
  • medicines to calm or reduce anxiety, or for sleep problems
  • medicines for hay fever, rashes or other allergies that can make you sleepy (sedative antihistamines, such as chlorphenamine or promethazine)
  • strong painkillers (such as codeine, methadone, morphine, oxycodone, pethidine or tramadol)
  • erythromycin or clarithromycin (antibiotics used to treat infections)
  • medicines used to treat fungal infections (such as ketoconazole and itraconazole)
  • ritonavir (a medicine used to treat HIV infections)

Mixing zopiclone with herbal remedies and supplements

Do not take any herbal remedies that make you feel sleepy while taking zopiclone.

They can increase the drowsy-making (sedating) effects of your medicine.